Acamprosate: How It Helps with Alcohol Dependence
Acamprosate is a medication used to help people stay abstinent after they stop drinking. It's often sold as Campral. Unlike drugs that stop cravings instantly, acamprosate works by rebalancing brain chemicals changed by long-term alcohol use. It's not a cure, but it lowers the urge to drink and helps reduce relapse risk.
How fast it helps varies. Most people start acamprosate after detox, once they are sober for a few days. The full benefit appears after weeks, not hours, so you need patience and regular dosing. Take it exactly as prescribed, even if you feel better.
How to use and common doses
Typical adult dose in many countries is 666 mg three times daily (two 333 mg tablets each time). Doctors may adjust the dose for kidney problems. Don't take more than recommended. If you miss a dose, take the next one when scheduled — don't double up. With severe kidney disease, your doctor may change or stop the medicine.
Common side effects include diarrhea, nausea, and headache. These often ease in the first few weeks. Serious reactions are rare but report rash, swelling, or severe mood changes right away. Acamprosate doesn't cause sedation or addiction, so it's safer than some other options for long-term use.
It's usually safe with many medicines, but tell your doctor about antidepressants, anticonvulsants, and any OTC supplements. Alcohol must be stopped before starting. Pregnant women should discuss risks — acamprosate hasn't been shown to help fetuses and other treatments may be preferred. Breastfeeding advice varies - ask your prescriber.
Practical tips and pairing with therapy
Medication works best with counseling and support groups. Schedule regular check-ins so your doctor can monitor kidney function and mood. Keep a daily pill habit — use a pillbox or phone alarms. If cravings spike, contact your care team; sometimes adding naltrexone or behavioral therapy gives extra support.
Your doctor will check kidney function before starting and periodically after. If creatinine rises or urine output drops, the dose may be reduced or stopped. Mental health should be watched too - if you notice worsening depression or new suicidal thoughts get help immediately. Keep all follow-up appointments.
Generic acamprosate is widely available and usually cheaper than brand-name versions. Many pharmacies stock it, and legitimate online pharmacies sell it with a prescription. Avoid suppliers that promise no-prescription delivery.
Can you drink while taking acamprosate? No - the drug is meant for people who already stopped drinking. If you relapse, tell your doctor so they can reassess. Do you need other meds? Sometimes doctors use acamprosate with naltrexone or disulfiram depending on goals and medical history.
Want to know if acamprosate is right for you? Bring a list of current meds, your drinking history, and any kidney or mental health issues to your appointment. Honest talk helps your prescriber choose the safest, most effective plan. If you start acamprosate, keep therapy as your main support - not the pill alone.
Talk openly with your provider, follow the dosing plan, pair acamprosate with counseling, and call your clinic if anything worries you today.
